0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Consolidated Statements of Operations and Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Consolidated Statements of Operations and Comprehensive Loss (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Consolidated Statements of Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Consolidated Statements of Stockholders' Equity (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952158 - Statement - Consolidated Statements of Cash Flows (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Acquisition, License Agreement and Research and Development Funding Collaboration Agreement link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Collaboration Agreements link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Balance Sheet Components link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Common Stock link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Stock-Based Awards link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Defined Contribution Plan link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Net Loss and Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Divestiture of Preclinical Small Molecule Programs link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Collaboration Agreements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Balance Sheet Components (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Stock-Based Awards (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Net Loss and Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Significant Accounting Policies - Concentration of Credit Risk and Other Risks and Uncertainties (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Significant Accounting Policies - Convertible Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Significant Accounting Policies - Investments (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Significant Accounting Policies - Cash, Cash Equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Significant Accounting Policies - Schedule of Property and Equipment, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Fair Value Measurements - Schedule of Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Marketable Securities - Schedule of Available for Sale Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Marketable Securities - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Acquisition, License Agreement and Research and Development Funding Collaboration Agreement - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Collaboration Agreements - Biogen (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Collaboration Agreements - Sanofi (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Collaboration Agreements - Takeda (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Collaboration Agreements - Schedule of Collaboration Revenue (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Collaboration Agreements - Schedule of Cost Sharing Payments and Reimbursements (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Balance Sheet Components - Schedule of Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Balance Sheet Components - Schedule of Property and Equipment, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Balance Sheet Components - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Balance Sheet Components - Schedule of Accrued Expenses and Other Current Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Commitments and Contingencies - Schedule of Summarizes Lease Costs (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Commitments and Contingencies - Schedule of Supplemental Lease Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Commitments and Contingencies - Schedule of Company's Future Minimum Lease Commitments (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Commitments and Contingencies - Schedule of Company's Future Minimum Lease Commitments (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Common Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Stock-Based Awards - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Stock-Based Awards - Schedule of Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Stock-Based Awards - Schedule of Assumptions Used for Estimating the Fair Value of Stock Options Granted (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stock-Based Awards - Schedule of Restricted Stock Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Stock-Based Awards - Schedule of Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Defined Contribution Plan - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Income Taxes - Schedule of Provision for Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Income Taxes - Schedule of Effective Tax Rate Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Income Taxes - Schedule of Reconciliation of Unrecognized Tax Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Net Loss and Net Loss Per Share - Schedule of Calculation of Basic and Diluted Net Loss (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Net Loss and Net Loss Per Share - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Divestiture of Preclinical Small Molecule Programs (Details) link:presentationLink link:calculationLink link:definitionLink 9955559 - Disclosure - Segment Information (Details) link:presentationLink link:calculationLink link:definitionLink