SEC FORM 4 SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
FIL Ltd

(Last) (First) (Middle)
P.O. BOX H.M. 670

(Street)
HAMILTON D0 00000

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Denali Therapeutics Inc. [ DNLI ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
Officer (give title below) X Other (specify below)
See Remark 1
3. Date of Earliest Transaction (Month/Day/Year)
12/12/2017
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/12/2017 C 1,397,326 A (1) 1,814,208 D
Common Stock 12/12/2017 C 28,750 A (1) 1,842,958 D
Common Stock 12/12/2017 C 71,875 A (1) 1,914,833 D
Common Stock 12/12/2017 C 1,065,616 A (1) 1,383,774 I Asia Ventures III L.P.
Common Stock 12/12/2017 C 21,942 A (1) 1,405,716 I Asia Ventures III L.P.
Common Stock 12/12/2017 C 54,854 A (1) 1,460,570 I Asia Ventures III L.P.
Common Stock 12/12/2017 C 293,204 A (1) 380,597 I Japan Ventures I L.P.
Common Stock 12/12/2017 C 6,027 A (1) 386,624 I Japan Ventures I L.P.
Common Stock 12/12/2017 C 15,068 A (1) 401,692 I Japan Ventures I L.P.
Common Stock 12/12/2017 C 292,303 A (1) 379,427 I FIL Capital Investments (Mauritius) II Limited
Common Stock 12/12/2017 C 6,008 A (1) 385,435 I FIL Capital Investments (Mauritius) II Limited
Common Stock 12/12/2017 C 15,021 A (1) 400,456 I FIL Capital Investments (Mauritius) II Limited
Common Stock 12/12/2017 C 3,755 A (1) 4,876 I Asia Partners III L.P.
Common Stock 12/12/2017 C 77 A (1) 4,953 I Asia Partners III L.P.
Common Stock 12/12/2017 C 193 A (1) 5,146 I Asia Partners III L.P.
Common Stock 12/12/2017 C 662 A (1) 859 I Japan Partners I L.P.
Common Stock 12/12/2017 C 13 A (1) 872 I Japan Partners I L.P.
Common Stock 12/12/2017 C 34 A (1) 906 I Japan Partners I L.P.
Common Stock 12/12/2017 C 1,008 A (1) 1,308 I India Partners II L.P.
Common Stock 12/12/2017 C 20 A (1) 1,328 I India Partners II L.P.
Common Stock 12/12/2017 C 51 A (1) 1,379 I India Partners II L.P.
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 1,397,326 (1) (1) Common Stock 1,397,326 (1) 0 D
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 1,065,616 (1) (1) Common Stock 1,065,616 (1) 0 I Asia Ventures III L.P.
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 293,204 (1) (1) Common Stock 293,204 (1) 0 I Japan Ventures I L.P.
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 292,303 (1) (1) Common Stock 292,303 (1) 0 I FIL Capital Investments (Mauritius) II Limited
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 3,755 (1) (1) Common Stock 3,755 (1) 0 I Asia Partners III L.P.
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 662 (1) (1) Common Stock 662 (1) 0 I Japan Partners I L.P.
Series A-1 Convertible Preferred Stock (1) 12/12/2017 C 1,008 (1) (1) Common Stock 1,008 (1) 0 I India Partners II L.P.
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 28,750 (1) (1) Common Stock 28,750 (1) 0 D
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 21,942 (1) (1) Common Stock 21,942 (1) 0 I Asia Ventures III L.P.
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 6,027 (1) (1) Common Stock 6,027 (1) 0 I Japan Ventures I L.P.
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 6,008 (1) (1) Common Stock 6,008 (1) 0 I FIL Capital Investments (Mauritius) II Limited
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 77 (1) (1) Common Stock 77 (1) 0 I Asia Partners III L.P.
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 13 (1) (1) Common Stock 13 (1) 0 I Japan Partners I L.P.
Series A-2 Convertible Preferred Stock (1) 12/12/2017 C 20 (1) (1) Common Stock 20 (1) 0 I India Partners II L.P.
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 71,875 (1) (1) Common Stock 71,875 (1) 0 D
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 54,854 (1) (1) Common Stock 54,854 (1) 0 I Asia Ventures III L.P.
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 15,068 (1) (1) Common Stock 15,068 (1) 0 I Japan Ventures I L.P.
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 15,021 (1) (1) Common Stock 15,021 (1) 0 I FIL Capital Investments (Mauritius) II Limited
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 193 (1) (1) Common Stock 193 (1) 0 I Asia Partners III L.P.
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 34 (1) (1) Common Stock 34 (1) 0 I Japan Partners I L.P.
Series B-1 Convertible Preferred Stock (1) 12/12/2017 C 51 (1) (1) Common Stock 51 (1) 0 I India Partners II L.P.
Explanation of Responses:
1. On December 12, 2017, in connection with the completion of the issuer's initial public offering, each share of Convertible Preferred Stock converted into one share of Common Stock.
Remarks:
Remark 1: Pandanus Partners, L.P. ("Pandanus") owns shares of FIL Limited ("FIL") voting stock. While the percentage of total voting power represented by these shares of FIL voting stock may fluctuate as a result of changes in the total number of shares of FIL voting stock outstanding from time to time, it normally represents more than 25% and less than 48.5% of the total votes which may be cast by all holders of FIL voting stock. Pandanus Associates, Inc. ("PAI") acts as general partner of Pandanus. Pandanus is owned by trusts for the benefit of members of the Johnson family, including FIL's Chairman Abigail P. Johnson, but disclaims that any such member is a beneficial owner of the securities reported on this form. The address of Pandanus is c/o FIL Limited, 42 Crow Lane, Hamilton, Bermuda, HM19. Remark 2: The filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, the undersigned are the beneficial owners of any securities reported herein Remark 3: The general partner of Asia Ventures III L.P. is Asia Partners III L.P. The general partner of Japan Ventures I L.P. is Japan Partners I L.P. FIL Capital Investments (Mauritius) II Limited is wholly owned by FIL India Ventures II L.P., the general partners of which are India Partners II L.P. and FIL Management India Ventures (Mauritius) Limited. The general partner of Asia Partners III L.P., Japan Partners I L.P. and India Partners II L.P. is FIL Capital Management Ltd., a wholly owned subsidiary of FIL. FIL Management India Ventures (Mauritius) Limited is wholly owned by FIL Asia Ventures Limited, a wholly owned subsidiary of FIL.
Marc R. Bryant, Duly authorized under Powers of Attorney effective as of September 16, 2015, by and on behalf of FIL Limited and its direct and indirect subsidiaries, Pandanus Partners, L.P. and Pandanus Associates, Inc. 12/14/2017
** Signature of Reporting Person Date
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